SIDE EFFECTS

WARNING: LOW WHITE BLOOD CELL COUNT (NEUTROPENIA)

  • Do not take ABRAXANE if your white blood cell count is below
    1,500 cells/mm3 (neutropenia), since you may be more likely to get a serious infection. While taking ABRAXANE, you must get regular blood tests to check for any problems that could develop
  • ABRAXANE contains albumin, a substance found in human blood. ABRAXANE should not be substituted for other paclitaxel formulations

If you are considering ABRAXANE, you should be aware that there are side effects associated with this treatment. The following important side effects were reported in ABRAXANE clinical trials. However, you may experience other side effects that are less common. Always remember to report any side effects you may have to your doctor or nurse.

Abraxane may cause serious side effects:

Decreased blood cell counts

A decrease in white blood cell counts (neutropenia) may lead to infections

ABRAXANE can cause a severe decrease in neutrophils (a type of white blood cells important in fighting against bacterial infections) and platelets (important for clotting and to control bleeding). Your doctor will check your blood cell count during your treatment with ABRAXANE and after you have stopped your treatment.

Call your doctor or nurse right away if you experience a fever over 100.4° F or notice any other signs of infection.

Find tips that may help

Neuropathy

Neuropathy is numbness, tingling, pain or weakness in your hands or feet.

Find tips that may help

Allergic reactions

Hypersensitivity reactions can be severe and sometimes fatal.

Most common side effects with ABRAXANE

+ Expand All
Hair loss

It is very likely that you will lose your hair when you take ABRAXANE. This may involve the loss of eyebrows, eyelashes, and pubic hair, as well as hair on your head. It can occur shortly after treatment has begun. Hair usually grows back after ABRAXANE treatment is completed.

Find tips that may help

Talk with your doctor or nurse if you experience these side effects.

Neuropathy

Numbness, pain, or weakness in the hands or feet.

Abnormal heartbeat

ABRAXANE may cause your heart to beat a little faster or slower than it normally does.

Find tips that may help

Talk with your doctor or nurse if you experience these side effects.

Tiredness

Make sure you get plenty of rest throughout your treatment. Talk to your doctor or nurse about ways to keep your energy level from decreasing too much during treatment. Tiredness is likely to improve once your treatment is over.

Find tips that may help

Talk with your doctor or nurse if you experience these side effects.

Joint and muscle pain

You may get joint and muscle pain a few days after your ABRAXANE treatment. These symptoms may disappear in a few days. Although pain medicine may not be necessary, tell your doctor or nurse if you are uncomfortable.

Talk with your doctor or nurse if you experience these side effects.

Changes in liver function TESTS

ABRAXANE may affect your liver. If this occurs, your skin or the whites of your eyes may look yellow, or you may notice a darker color of your urine. If you already have liver problems before starting treatment, your doctor may reduce the amount of ABRAXANE that you get.

Talk with your doctor or nurse if you experience these side effects.

Anemia

Red blood cells carry oxygen to all parts of your body. Having too few red blood cells to carry the oxygen in your body is known as anemia. Anemia may make you feel tired, appear pale, and experience shortness of breath. Be sure to talk to a member of your healthcare team if you experience any of these symptoms.

Call your doctor or nurse if you feel weak, tired, or short of breath. They can talk with you about further treatment for anemia.

Find tips that may help

Nausea and vomiting

If you experience any nausea (feeling sick to your stomach) after you have received ABRAXANE, tell your doctor or nurse. Your doctor may prescribe a medicine that can help reduce these symptoms.

If you experience severe abdominal or stomach area pain and/or severe or chronic diarrhea, tell your doctor right away.

Find tips that may help

Infections

ABRAXANE can cause a drop in the number of white blood cells in your bloodstream, which may cause you to be more susceptible to infection and fever.

Find tips that may help

Diarrhea

Diarrhea may disappear without treatment. If you experience severe abdominal or stomach area pain and/or severe diarrhea, tell your doctor right away.

If you experience severe abdominal or stomach area pain and/or severe or chronic diarrhea, tell your doctor right away.

Find tips that may help

Loss of Body Fluid (Dehydration)
Swelling of Hands and Feet

These are not all of the possible side effects that can occur with ABRAXANE. Talk with your doctor about other possible side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Next: Important Safety Information

Important Safety Information

WARNING: LOW WHITE BLOOD CELL COUNT (NEUTROPENIA)

  • Do not take ABRAXANE if your white blood cell count is below 1,500 cells/mm3 (neutropenia), since you may be more likely to get a serious infection. While taking ABRAXANE, you must get regular blood tests to check for any problems that could develop
  • ABRAXANE contains albumin, a substance found in human blood. Do not substitute for or with other paclitaxel formulations
  • Do not receive ABRAXANE if:
    • your white blood cell count is below 1500 cells/mm³
    • you have had a severe allergic reaction to ABRAXANE
  • ABRAXANE may cause serious side effects, including:
    • decreased blood counts. ABRAXANE can cause a severe decrease in neutrophils (a type of white blood cell important in fighting against bacterial infections) and platelets (important for clotting and to control bleeding). Your doctor will check your blood cell count during your treatment with ABRAXANE and after you have stopped your treatment
    • numbness, tingling, pain, or weakness in the hands or feet (neuropathy)
    • allergic (hypersensitivity) reactions, which could be severe and sometimes fatal, have been reported with ABRAXANE
  • Treatment with ABRAXANE can make liver problems worse. If you have liver problems, your starting dose of ABRAXANE should be lowered or withheld
  • ABRAXANE contains albumin (human), a product of human blood
  • If you are pregnant or become pregnant, ABRAXANE can harm your unborn baby. You should not become pregnant while taking ABRAXANE. Women who may become pregnant should use effective birth control (contraception). Talk to your doctor about the best way to prevent pregnancy while receiving ABRAXANE
  • If you are a man, you should not father a child during your treatment with ABRAXANE. ABRAXANE can harm the unborn baby of your partner
  • The most common side effects of ABRAXANE include:
    • hair loss
    • numbness, tingling, pain, or weakness in the hands or feet
    • abnormal heart beat
    • tiredness
    • joint and muscle pain
    • changes in your liver function tests
    • rash
    • low red blood cell count (anemia). Red blood cells carry oxygen to your body tissues. Tell your doctor if you feel weak, tired, or short of breath
    • nausea and vomiting
    • infections. If you have a fever (temperature of greater than 100.4ºF) or other signs of infection, tell your doctor right away
    • diarrhea
    • loss of body fluid (dehydration)
    • swelling in the hands or feet
  • Other side effects include vision problems, decreased appetite, kidney problems, constipation, and difficulty breathing
  • In some patients receiving ABRAXANE, severe heart and blood vessel side effects have occurred. These included chest pain, heart attack, fluid under the skin, blood clots in the veins or lungs, high blood pressure, stroke, and heart failure
  • You should contact your doctor if you have signs or symptoms of vomiting, diarrhea, dehydration, cough, or breathing difficulties that do not go away, or signs of an allergic reaction. Tell your doctor if you have any other medical conditions
  • Treatment with ABRAXANE can cause irritation where the medicine is injected (injection site reactions). You should be monitored by your doctor or nurse during and after you receive ABRAXANE to make sure no problems occur at the injection site. In some cases, these problems occurred 7 to 10 days after the medicine was injected
  • It is not known whether ABRAXANE interacts with other drugs, so be sure to tell your doctor about any medicines, including prescription and over-the-counter medicines, vitamins, and herbal supplements you are taking
  • Since it is not known if ABRAXANE passes into human milk, you should discuss with your doctor if you should receive ABRAXANE or breastfeed
  • It is not known if ABRAXANE is safe or effective in children
  • ABRAXANE has not been studied in people with kidney problems

These are not all the possible side effects of ABRAXANE. For more information, ask your doctor or pharmacist. You may report side effects to FDA at 1-800-FDA-1088.

Please see full Prescribing Information, including Boxed WARNING.

Expand

IMPORTANT SAFETY INFORMATION

WARNING: LOW WHITE BLOOD CELL COUNT (NEUTROPENIA)

  • Do not take ABRAXANE if your white blood cell count is below 1,500 cells/mm3 (neutropenia), since you may be more likely to get a serious infection. While taking ABRAXANE, you must get regular blood tests to check for any problems that could develop
  • ABRAXANE contains albumin, a substance found in human blood. Do not substitute for or with other paclitaxel formulations
  • Do not receive ABRAXANE if:
    • your white blood cell count is below 1500 cells/mm³
    • you have had a severe allergic reaction to ABRAXANE
  • ABRAXANE may cause serious side effects, including:
    • decreased blood counts. ABRAXANE can cause a severe decrease in neutrophils (a type of white blood cell important in fighting against bacterial infections) and platelets (important for clotting and to control bleeding). Your doctor will check your blood cell count during your treatment with ABRAXANE and after you have stopped your treatment
    • numbness, tingling, pain, or weakness in the hands or feet (neuropathy)
    • allergic (hypersensitivity) reactions, which could be severe and sometimes fatal, have been reported with ABRAXANE
  • Treatment with ABRAXANE can make liver problems worse. If you have liver problems, your starting dose of ABRAXANE should be lowered or withheld
  • ABRAXANE contains albumin (human), a product of human blood
  • If you are pregnant or become pregnant, ABRAXANE can harm your unborn baby. You should not become pregnant while taking ABRAXANE. Women who may become pregnant should use effective birth control (contraception). Talk to your doctor about the best way to prevent pregnancy while receiving ABRAXANE
  • If you are a man, you should not father a child during your treatment with ABRAXANE. ABRAXANE can harm the unborn baby of your partner
  • The most common side effects of ABRAXANE include:
    • hair loss
    • numbness, tingling, pain, or weakness in the hands or feet
    • abnormal heart beat
    • tiredness
    • joint and muscle pain
    • changes in your liver function tests
    • rash
    • low red blood cell count (anemia). Red blood cells carry oxygen to your body tissues. Tell your doctor if you feel weak, tired, or short of breath
    • nausea and vomiting
    • infections. If you have a fever (temperature of greater than 100.4ºF) or other signs of infection, tell your doctor right away
    • diarrhea
    • loss of body fluid (dehydration)
    • swelling in the hands or feet
  • Other side effects include vision problems, decreased appetite, kidney problems, constipation, and difficulty breathing
  • In some patients receiving ABRAXANE, severe heart and blood vessel side effects have occurred. These included chest pain, heart attack, fluid under the skin, blood clots in the veins or lungs, high blood pressure, stroke, and heart failure
  • You should contact your doctor if you have signs or symptoms of vomiting, diarrhea, dehydration, cough, or breathing difficulties that do not go away, or signs of an allergic reaction. Tell your doctor if you have any other medical conditions
  • Treatment with ABRAXANE can cause irritation where the medicine is injected (injection site reactions). You should be monitored by your doctor or nurse during and after you receive ABRAXANE to make sure no problems occur at the injection site. In some cases, these problems occurred 7 to 10 days after the medicine was injected
  • It is not known whether ABRAXANE interacts with other drugs, so be sure to tell your doctor about any medicines, including prescription and over-the-counter medicines, vitamins, and herbal supplements you are taking
  • Since it is not known if ABRAXANE passes into human milk, you should discuss with your doctor if you should receive ABRAXANE or breastfeed
  • It is not known if ABRAXANE is safe or effective in children
  • ABRAXANE has not been studied in people with kidney problems

These are not all the possible side effects of ABRAXANE. For more information, ask your doctor or pharmacist. You may report side effects to FDA at 1-800-FDA-1088.

Please see full Prescribing Information, including Boxed WARNING.

FOR HEALTHCARE PROFESSIONALS

The information contained in this section of ABRAXANE.com is technical in nature and is intended for US healthcare professionals only.

If you are not a US healthcare professional, click "CANCEL" below to return to the patient and caregiver section of the site. Click "OK" if you are a healthcare professional.

OKCANCEL
YOU ARE NOW LEAVING ABRAXANE.COM

The content of the linked site is the sole responsibility of the site provider.

Celgene Corporation does not control or endorse this third-party website.

Click "OK" to proceed or "CANCEL" to return to ABRAXANE.com.

OKCANCEL
EMAIL INFORMATION

Complete the form fields below to share this page.

SEND CANCEL
Loading...